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Table of Contents > Abs + Ref
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Korean J Parasitol. 2006 Mar;44(1):81-86.
Published online 2006 March 20.  doi: 10.3347/kjp.2006.44.1.81.
Copyright © 2006 by The Korean Society for Parasitology
Four cases of gastric submucosal mass suspected as anisakiasis
Seoung-Gu Kim,1 Yun-Ju Jo,1 Young-Sook Park,1 Sung-Hwan Kim,1 Moon-Hee Song,1 Han-Hyo Lee,1 Jeong-Seon Kim,1 Ji-Won Ryou,1 Jong-Eun Joo,2 and Dong-Hoon Kim2
1Department of Internal Medicine, Eulji University College of Medicine, Seoul, 139-711, Korea.
2Department of Pathology, Eulji University College of Medicine, Seoul, 139-711, Korea.

Corresponding author (Email: jyj1138@eulji.or.kr )
Received October 04, 2005; Accepted November 28, 2005.

 This article has been cited by 1 article in  


Abstract

Anisakiasis is a parasitic disease caused by ingestion of raw fish infected with anisakid larvae. Endoscopic changing patterns of submucosal lesions in chronic gastric anisakiasis have not been known yet. Here we report 4 cases of suspected gastric anisakiasis which were improved during follow-up periods without surgical treatment. The patients presented with abdominal pain, nausea and vomiting after consuming raw marine fish, and visited our gastroenterology outpatient department. Their endoscopic findings showed firm and yellowish submucosal masses accompanied with eccentric erosions. Histologic findings showed severe eosinophilic infiltrations. In blood tests, peripheral eosinophil counts and total IgE levels were elevated. We believed that all cases were caused by larval anisakid infections. The submucosal mass lesions disappeared during the follow-up periods of 2 to 4 mo.

Keywords: Anisakis, parasite, submucosal tumor, stomach, case report.
References
1. Alonso-Gomez A,Moreno-Ancillo A,Lopez-Serrano MC,Suarez-de-Parga JM,Daschner A,Caballero MT,Barranco P,Cabanas R. Anisakis simplex only provokes allergic symptoms when the worm parasitises the gastrointestinal tract. Parasitol Res 2004;93:378–384.
2. Caballero ML,Moneo I. Specific IgE determination to Ani s 1, a major allergen from Anisakis simplex, is a useful tool for diagnosis. Ann Allergy Asthma Immunol 2002;89:74–77.
3. Castan B,Borda F,Inarrairaegui M,Pastor G,Vila J,Zozaya JM. Digestive anisakiasis: clinical manifestations and diagnosis according to localization. Rev Esp Enferm Dig 2002;94:463–472.
4. Dziekonska-Rynko J,Rokicki J,Jablonowski Z. Influence of infection with III larval stage of Anisakis simplex on the activity of proteases in alimentary tract of guinea pigs. Wiad Parazytol 1997;43:425–430.
5. Dziekonska-Rynko J,Rokicki J,Jablonowski Z. Effects of ivermectin and albendazole against Anisakis simplex in vitro and in guinea pigs. J Parasitol 2002;88:395–398.
6. Im KI,Shin HJ,Kim BH,Moon SI. Gastric anisakiasis cases in Cheju-do, Korea. Korean J Parasitol 1995;33:179–186.
7. Kim CH,Chung BS,Moon YI,Chun SH. A case report on human infection with Anisakis sp. in Korea. Koeran J Parasitol 1971;9:39–43.
8. Ko GH,Park CK,Kong HJ,Choi CS,Lee SH,Hong SJ. Intestinal anisakiasis. Korean J Pathol 1988;22:154–158.
9. Kojima K. Parasitic granuloma with special reference to histopathological findings of the Anisakis-like larva infection. Jap J Parasitol 1966;15:30–31.
10. Lee HS,Park KS,Jung KT,Yoo SJ,Kho JH,Park PS,Choi WS,Choi DY,Choi HS. A Case of chronic gastric anisakiasis with massive bleeding. Korean J Gastrointest Endosc 1993;13:697–700.
11. Lee MS,Kim YS,Kang JH,Park EJ,Cho YB,Sim CS. 2 Cases of submucosal tumors caused by gastric anisakiasis. Korean J Gastrointest Endosc 1999;19:67–72.
12. Lee KH,Koo JT,Song JH,Hyun MS,Jhi CJ. Acute gastric anisakiasis - endoscopic, radiologic diagnosis and its management. Korean J Intern Med 1981;24:1220–1227.
13. Moore DA,Girdwood RW,Chiodini PL. Treatment of anisakiasis with albendazole. Lancet 2002;360:54.
14. Seol SY,Ok SC,Pyo JS,Kim IH,Lee SH,Chung JM,Choi HJ,Jeong SJ,Sohn WM. Twenty cases of gastric anisakiasis caused by Anisakis type I larva. Korean J Gastroenterol 1994;26:17–24.
15. Shim YR,Kim DS,Lee TS. Ileal anisakiasis: A report of two cases. Korean J Pathol 1995;29:91–95.
16. Song TJ,Cho SW,Joo KH. Endoscopic findings of aucte gastric anisakiasis - Thirty-nine cases in Inchon City. Korean J Gastrointest Endosc 1999;19:878–884.
17. Van Thiel PH,Kruipers FC,Roskam TH. A nematoede parasitic to herring, causing acute abdominal syndromes in man. Trop Geogr Med 1960;2:97–113.
18. Yoon WJ,Lee SM,Lee SH,Yoon YB. Gastric anisakiasis. Gastrointest Endosc 2004;59:400.