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Korean J Parasitol. 2009 Oct;47(Suppl):S59-S68.
Published online 2009 October 27.  doi: 10.3347/kjp.2009.47.S.S59.
Copyright © 2009 by The Korean Society for Parasitology
Functional Genes and Proteins of Clonorchis sinensis
Tae Im Kim,1 Byoung-Kuk Na,2 and Sung-Jong Hong1
1Department of Medical Environmental Biology and Research Center for Biomolecules and Biosystems, Chung-Ang University College of Medicine, Seoul 156-756, Korea.
2Department of Parasitology and Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju 660-751, Korea.

Corresponding author (Email: hongsj@cau.ac.kr )
Received October 06, 2009; Revised October 08, 2009; Accepted October 08, 2009.

Abstract

During the past several decades, researches on parasite genetics have progressed from biochemical and serodiagnostic studies to protein chemistry, molecular biology, and functional gene studies. Nowadays, bioinformatics, genomics, and proteomics approaches are being applied by Korean parasitology researchers. As for Clonorchis sinensis, investigations have been carried out to identify its functional genes using forward and reverse genetic approaches and to characterize the biochemical and biological properties of its gene products. The authors review the proteins of cloned genes, which include antigenic proteins, physiologic and metabolic enzymes, and the gene expression profile of Clonorchis sinensis.

Keywords: Clonorchis sinensis, functional genes, chromosome, antioxidant enzyme, protease, energy metabolism, antigenic proteins.
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