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Korean J Parasitol. 2009 Oct;47(Suppl):S143-S153.
Published online 2009 October 26.  doi: 10.3347/kjp.2009.47.S.S143.
Copyright © 2009 by The Korean Society for Parasitology
Household Arthropod Allergens in Korea
Tai-Soon Yong, and Kyoung Yong Jeong
Department of Environmental Medical Biology, Institute of Tropical Medicine and Arthropods of Medical Importance Resource Bank, Yonsei University College of Medicine, Seoul 120-752, Korea.

Corresponding author (Email: tsyong212@yuhs.ac )
Received August 22, 2009; Revised September 28, 2009; Accepted September 28, 2009.

Abstract

Arthropods are important in human health, which can transmit pathogens to humans, parasitize, or produce important allergens. Allergy prevalence becomes higher in Korea recently as well as other developed countries in contrast to a decrease of infectious diseases. Allergic diseases caused by household arthropods have increased dramatically during the last few decades since human beings spend more their time for indoor activities in modernized life style. Household arthropods are one of the most common causes of allergic diseases. Biological characterization of household arthropods and researches on their allergens will provide better understanding of the pathogenesis of allergic diseases and suggest new therapeutic ways. Therefore, studies on arthropods of allergenic importance can be considered one of the major research areas in medical arthropodology and parasitology. Here, the biology of several household arthropods, including house dust mites and cockroaches, the 2 most well known arthropods living indoor together with humans worldwide, and characteristics of their allergens, especially the research activities on these allergens performed in Korea, are summarized.

Keywords: allergen, allergy, arthropod, cockroach, insect, mite.
References
1. Guerrant RL,Walker DH,Weller PF. Tropical infectious diseases; principles, pathogenesis, & practice. 2nd ed. Philadelphia, USA: Elsevier Churchill Livingston; 2006. pp. 77-81.
2. Ree HI. Medical Entomology. 4th ed. Seoul, Korea: Komunsa; 2005. pp. 362-366.
3. Jeong KY,Hong CS,Yong TS. Domestic arthropods and their allergens. Protein Pept Lett 2007;14:934–942.
4. Linneberg A. Are we getting enough allergens?. Int Arch Allergy Immunol 2008;147:93–100.
5. Ibarrola I,Arilla MC,Herrero MD,Esteban MI,Martinez A,Asturias JA. Expression of a recombinant protein immunochemically equivalent to the major Anisakis simplex allergen Ani s 1. J Investig Allergol Clin Immunol 2008;18:78–83.
6. Gaffin JM,Phipatanakul W. The role of indoor allergens in the development of asthma. Curr Opin Allergy Clin Immunol 2009;9:128–135.
7. Mantyjarvi R,Rautiainen J,Virtanen T. Lipocalins as allergens. Biochim Biophys Acta 2000;1482:308–317.
8. Trompette A,Divanovic S,Visintin A,Blanchard C,Hedge RS,Madan R,Thorne PS,Wills-Karp M,Giovannini TL,Weiss JP,Karp CL. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009;457:585–588.
9. Chapman MD,Wunschmann S,Pomes A. Proteases as Th2 adjuvants. Curr Allergy Asthma Rep 2007;7:363–367.
10. Jeong KY,Hong CS,Yong TS. Recombinant allergens for diagnosis and immunotherapy of allergic disorders, with emphasis on cockroach allergy. Curr Protein Pept Sci 2006;7:57–71.
11. Pomes A,Wunschmann S,Hindley J,Vailes LD,Chapman MD. Cockroach allergens: function, structure and allergenicity. Protein Pept Lett 2007;14:960–969.
12. Jeong SK,Kim HJ,Youm JK,Ahn SK,Choi EH,Sohn MH,Kim KE,Hong JH,Shin DM,Lee SH. Mite and cockroach allergens activate protease-activated receptor 2 and delay epidermal permeability barrier recovery. J Invest Dermatol 2008;128:1930–1939.
13. O'Neil SE,Heinrich TK,Hales BJ,Hazell LA,Holt DC,Fischer K,Thomas WR. The chitinase allergens Der p 15 and Der p 18 from Dermatophagoides pteronyssinus. Clin Exp Allergy 2006;36:831–839.
14. Shuhui L,Mok YK,Wong WS. Role of mammalian chitinases in asthma. Int Arch Allergy Immunol 2009;149:369–377.
15. Taylor SL,Lehrer SB. Principles and characteristics of food allergens. Crit Rev Food Sci Nutr 1996;36:S91–S118.
16. Lee WK,Cho BK. An ecological study on the house dust mite. Korean J Dermatol 1984;22:286–294.
17. Ree HI,Jeon SH,Lee IY,Hong CS,Lee DK. Fauna and geographical distribution of house dust mites in Korea. Korean J Parasitol 1997;35:9–17.
18. Hong CS. House dust mites and clinical allergy. J Korean Soc Allergol 1991;11:297–308.
19. Park JW,Kim CW,Kang DB,Lee IY,Choi SY,Yong TS,Shin DC,Kim KE,Hong CS. Low-flow, long-term air sampling under normal domestic activity to measure house dust mite and cockroach allergens. J Investig Allergol Clin Immunol 2002;12:293–298.
20. Thomas WR,Heinrich TK,Smith WA,Hales BJ. Pyroglyphid house dust mite allergens. Protein Pept Lett 2007;14:943–953.
21. Park JW,Hong CS,Ko SH,Kim CW. IL-5 and IL-10 production of peripheral blood mononuclear cells by stimulation of D. farinae antigen in atopic asthmatics. J Asthma Allergy Clin Immunol 1999;19:557–565.
22. Lee JS,Kim IS,Ryu JS,Yun CY. House dust mite, Dermatophagoides pteronyssinus increases expression of MCP-1, IL-6, and IL-8 in human monocytic THP-1 cells. Cytokine 2008;42:365–371.
23. Ghaemmaghami AM,Robins A,Gough L,Sewell HF,Shakib F. Human T cell subset commitment determined by the intrinsic property of antigen: the proteolytic activity of the major mite allergen Der p 1 conditions T cells to produce more IL-4 and less IFN-γ. Eur J Immunol 2001;31:1211–1216.
24. Oh JW,Lee HB,Chung YH,Choi Y,Song MK. The difference of interleukin-4 and interferon-γ production of Der p 1 stimulated T cells and effects of immunomodulator in house dust mite sensitive atopic and non-atopic individuals. J Asthma Allergy Clin Immunol 1999;19:548–556.
25. Park GM,Lee SM,Lee IY,Ree HI,Kim KS,Hong CS,Yong TS. Localization of a major allergen, Der p 2, in the gut and faecal pellets of Dermatophagoides pteronyssinus. Clin Exp Allergy 2000;30:1293–1297.
26. Jeong KY,Lee IY,Ree HI,Hong CS,Yong TS. Localization of Der f 2 in the gut and fecal pellets of Dermatophagoides farinae. Allergy 2002;57:729–731.
27. Jin HS,Yong TS,Park JW,Hong CS,Oh SH. Immune reactivity of recombinant group 2 allergens of house dust mite, Dermatophagoides pteronyssinus, and Dermatophagoides farinae. J Investig Allergol Clin Immunol 2003;13:36–42.
28. Jeong KY,Jin HS,Oh SH,Hong CS,Lee IY,Ree HI,Yong TS. Monoclonal antibodies to recombinant Der f 2 and development of a two-site ELISA sensitive to major Der f 2 isoallergen in Korea. Allergy 2002;57:29–34.
29. Yong TS,Lee SM,Park GM,Lee IY,Ree HI,Kim KS,Oh SH,Park JW,Hong CS. Monoclonal antibodies to recombinant Der p 2, a major house dust mite allergen: specificity, epitope analysis and development of two-site capture ELISA. Korean J Parasitol 1999;37:163–169.
30. Park JW,Kim KS,Jin HS,Kim CW,Kang DB,Choi SY,Yong TS,Oh SH,Hong CS. Der p 2 isoallergens have different allergenicity, and quantification with 2-site ELISA using monoclonal antibodies is influenced by the isoallergens. Clin Exp Allergy 2002;32:1042–1047.
31. Park SY,Cho JH,Oh DY,Park JW,Ahn MJ,Han JS,Oh JW. House dust mite allergen Der f 2-induced phospholipase D1 activation is critical for the production of interleukin-13 through activating transcription factor-2 activation in human bronchial epithelial cells. J Biol Chem 2009;284:20099–20110.
32. Kim YK,Oh SY,Oh HB,Lee BJ,Son JW,Cho SH,Kim YY,Min KU. Positive association between HLA-DRB1*07 and specific IgE responses to purified major allergens of D. pteronyssinus (Der p 1 and Der p 2). Ann Allergy Asthma Immunol 2002;88:170–174.
33. Aki T,Kodama T,Fujikawa A,Miura K,Shigeta S,Wada T,Jyo T,Murooka Y,Oka S,Ono K. Immunochemical characterization of recombinant and native tropomyosins as a new allergen from the house dust mite, Dermatophagoides farinae. J Allergy Clin Immunol 1995;96:74–83.
34. Asturias JA,Arilla MC,Gómez-Bayón N,Martínez A,Martínez J,Palacios R. Sequencing and high level expression in Escherichia coli of the tropomyosin allergen (Der p 10) from Dermatophagoides pteronyssinus. Biochim Biophys Acta 1998;1397:27–30.
35. Revsbech P,Dueholm M. Storage mite allergy among bakers. Allergy 1990;45:204–208.
36. Park JW,Ko SH,Yong TS,Ree HI,Jeoung BJ,Hong CS. Cross-reactivity of Tyrophagus putrescentiae with Dermatophagoides farinae and Dermatophagoides pteronyssinus in urban areas. Ann Allergy Asthma Immunol 1999;83:533–539.
37. Vidal C,Boquete O,Gude F,Rey J,Meijide LM,Fernandez-Merino MC,Gonzalez-Quintela A. High prevalence of storage mite sensitization in a general adult population. Allergy 2004;59:401–405.
38. Choi DR,Kim HS,Koh CO,Kim HS,Yoon HS,Park YB,Kim SH,Lee JY. A case of bronchial asthma due to Tyrophagus putrescentiae in a non occupational setting. J Asthma Allergy Clin Immunol 2004;24:141–145.
39. Fernandez-Caldas E,Lockey RF. Blomia tropicalis, a mite whose time has come. Allergy 2004;59:1161–1164.
40. Chua KY,Cheong N,Kuo IC,Lee BW,Yi FC,Huang CH,Liew LN. The Blomia tropicalis allergens. Protein Pept Lett 2007;14:325–333.
41. Hart BJ,Whitehead L. Ecology of house dust mites in Oxfordshire. Clin Exp Allergy 1990;20:203–209.
42. Franz JT,Masuch G,Musken H,Bergmann KC. Mite fauna of German farms. Allergy 1997;52:1233–1237.
43. Musken H,Franz JT,Wahl R,Paap A,Cromwell O,Masuch G,Bergmann KC. Sensitization to different mite species in German farmers: clinical aspects. J Investig Allergol Clin Immunol 2000;10:346–351.
44. Krol A,Krafchik B. The differential diagnosis of atopic dermatitis in childhood. Dermatol Ther 2006;19:73–82.
45. Groenewoud GC,de Graafin't Veld C,vVan Oorschot-van Nes AJ,de Jong NW,Vermeulen AM,van Toorenenbergen AW,Burdorf A,de Groot H,Gerth van Wijk R. Prevalence of sensitization to the predatory mite Amblyseius cucumeris as a new occupational allergen in horticulture. Allergy 2002;57:614–619.
46. Lee JY. Tyrophagus putrescentiae: an important allergen in Daejeon. J Asthma Allergy Clin Immunol 2002;22:703–710.
47. Ree HI,Lee IY. Development of mass rearing technique of Tyrophagus putrescentiae (Acari: Acaridae) found in house dust. Korean J Parasitol 1997;35:149–154.
48. Munhbayarlah S,Park JW,Ko SH,Ree HI,Hong CS. Identification of Tyrophagus putrescentiae allergens and evaluation of cross-reactivity with Dermatophagoides pteronyssinus. Yonsei Med J 1998;39:109–115.
49. Jeong KY,Kim WK,Lee JS,Lee J,Lee IY,Kim KE,Park JW,Hong CS,Ree HI,Yong TS. Immunoglobulin E reactivity of recombinant allergen Tyr p 13 from Tyrophagus putrescentiae homologous to fatty acid binding protein. Clin Diagn Lab Immunol 2005;12:581–585.
50. Jeong KY,Lee H,Lee JS,Lee J,Lee IY,Ree HI,Hong CS,Park JW,Yong TS. Immunoglobulin E binding reactivity of a recombinant allergen homologous to α-tubulin from Tyrophagus putrescentiae. Clin Diagn Lab Immunol 2005;12:1451–1454.
51. Jeong KY,Kim CR,Un S,Yi MH,Lee IY,Park JW,Hong CS,Yong TS. Allergenicity of recombinant troponin C from Tyrophagus putrescentiae. Int Arch Allergy Immunol 2010;151:207–213.
52. Jeong KY,Lee H,Lee JS,Lee J,Lee IY,Ree HI,Hong CS,Yong TS. Molecular cloning and the allergenic characterization of tropomyosin from Tyrophagus putrescentiae. Protein Pept Lett 2007;14:431–436.
53. Arruda LK. Cockroach allergens. Curr Allergy Asthma Rep 2005;5:411–416.
54. Yun YY,Ko SH,Park JW,Lee IY,Ree HI,Hong CS. Comparison of allergenic components between German cockroach whole body and fecal extracts. Ann Allergy Asthma Immunol 2001;86:551–556.
55. Kang BC,Wu CW,Johnson J. Characteristics and diagnoses of cockroach-sensitive bronchial asthma. Ann Allergy 1992;68:237–244.
56. Litonjua AA,Carey VJ,Burge HA,Weiss ST,Gold DR. Exposure to cockroach allergen in the home is associated with incident doctor-diagnosed asthma and recurrent wheezing. J Allergy Clin Immunol 2001;107:41–47.
57. Jeong KY,Lee IY,Lee J,Ree HI,Hong CS,Yong TS. Effectiveness of education for control of house dust mites and cockroaches in Seoul, Korea. Korean J Parasitol 2006;44:73–79.
58. Kim WK,Kim CH,Lee KE,Shon MH,Jang GC,Kim KE,Lee IY,Jeong KY,Lee JW,Yong TS,Kim CW,Park JW,Hong CS. Seasonal distribution of cockroaches, a major source of indoor allergens, in Seoul metropolitan area. J Asthma Allergy Clin Immunol 2002;22:728–735.
59. Lee SY,Kim KE,Kim DS,Kim DH,Lee KY. A study of antigen provocation test with German cockroach in atopic asthmatic children. Ped Allergy Respir Dis 1993;3:83–93.
60. Jeoung BJ,Ryu JW,Yum HY,Park JW,Hong CS,Lee HB,Yong TS,Kim KE,Lee KY. Identification and characterization of German cockroach allergen. Ped Allergy Respir Dis 1998;8:221–228.
61. Yong TS,Lee JS,Lee J,Park SJ,Jeon SH,Ree HI,Park JW. Identification and purification of IgE-reactive proteins in German cockroach extract. Yonsei Med J 1999;40:283–289.
62. Lee H,Jeong KY,Shin KH,Yi MH,Gantulaga D,Hong CS,Yong TS. Reactivity of German cockroach allergen, Bla g 2, peptide fragments to IgE antibodies in patients' sera. Korean J Parasitol 2008;46:243–246.
63. Shin KH,Jeong KY,Hong CS,Yong TS. IgE binding reactivity of peptide fragments of Bla g 4, a major German cockroach allergen. Korean J Parasitol 2009;47:31–36.
64. Jeong KY,Jeong KJ,Yi MH,Lee H,Hong CS,Yong TS. Allergenicity of sigma and delta class glutathione S-transferases from the German cockroach. Int Arch Allergy Immunol 2009;148:59–64.
65. Jeong KY,Lee H,Shin KH,Yi MH,Jeong KJ,Hong CS,Yong TS. Sequence polymorphisms of major German cockroach allergens Bla g 1, Bla g 2, Bla g 4, and Bla g 5. Int Arch Allergy Immunol 2009;145:1–8.
66. Sohn MH,Lee YA,Jeong KY,Sim S,Kim KE,Yong TS,Shin MH. German cockroach extract induces activation of human eosinophils to release cytotoxic inflammatory mediators. Int Arch Allergy Immunol 2004;134:141–149.
67. Hong JH,Lee SI,Kim KE,Yong TS,Seo JT,Sohn MH,Shin DM. German cockroach extract activates protease-activated receptor 2 in human airway epithelial cells. J Allergy Clin Immunol 2004;113:315–319.
68. Lee KE,Kim JW,Jeong KY,Kim KE,Yong TS,Sohn MH. Regulation of German cockroach extract-induced IL-8 expression in human airway epithelial cells. Clin Exp Allergy 2007;37:1364–1373.
69. Pomés A,Melén E,Vailes LD,Retief JD,Arruda LK,Chapman MD. Novel allergen structures with tandem amino acid repeats derived from German and American cockroach. J Biol Chem 1998;273:30801–30807.
70. Shao L,Devenport M,Fujioka H,Ghosh A,Jacobs-Lorena M. Identification and characterization of a novel peritrophic matrix protein, Ae-Aper50, and the microvillar membrane protein, AEG 12, from the mosquito, Aedes aegypti. Insect Biochem Mol Biol 2005;35:947–959.
71. Yi MH,Jeong KY,Kim CR,Yong TS. IgE-binding reactivity of peptide fragments of Bla g 1.02, a major German cockroach allergen. Asian Pac J Allergy Immunol 2009;27:121–129.
72. Eggleston PA,Rosenstreich D,Lynn H,Gergen P,Baker D,Kattan M,Mortimer KM,Mitchell H,Ownby D,Slavin R,Malveaux F. Relationship of indoor allergen exposure to skin test sensitivity in inner-city children with asthma. J Allergy Clin Immunol 1998;102:563–570.
73. Satinover SM,Reefer AJ,Pomes A,Chapman MD,Platts-Mills TA,Woodfolk JA. Specific IgE and IgG antibody-binding patterns to recombinant cockroach allergens. J Allergy Clin Immunol 2005;115:803–809.
74. Arruda LK,Vailes LD,Mann BJ,Shannon J,Fox JW,Vedvick TS,Hayden ML,Chapman MD. Molecular cloning of a major cockroach (Blattella germanica) allergen, Bla g 2. Sequence homology to the aspartic proteases. J Biol Chem 1995;270:19563–19568.
75. Platts-Mills TA,Vervloet D,Thomas WR,Aalberse RC,Chapman MD. Indoor allergens and asthma: report of the Third International Workshop. J Allergy Clin Immunol 1997;100:S2–S24.
76. Jeong KY,Yi MH,Jeong KJ,Lee H,Hong CS,Yong TS. Sequence diversity of the Bla g 4 cockroach allergen, homologous to lipocalins, from Blattella germanica. Int Arch Allergy Immunol 2009;148:339–345.
77. Asturias JA,Gómez-Bayón N,Arilla MC,Martínez A,Palacios R,Sánchez-Gascón F,Martínez J. Molecular characterization of American cockroach tropomyosin (Periplaneta americana allergen 7), a cross-reactive allergen. J Immunol 1999;162:4342–4348.
78. Sookrung N,Indrawattana N,Tungtrongchitr A,Bunnag C,Tantilipikorn P,Kwangsri S,Chaicump W. Allergenicity of native/recombinant tropomyosin, Per a 7, of American cockroach (CR), Periplaneta americana, among CR allergic Thais. Asian Pac J Allergy Immunol 2009;27:9–17.
79. Jeong KY,Lee J,Lee IY,Ree HI,Hong CS,Yong TS. Allergenicity of recombinant Bla g 7, German cockroach tropomyosin. Allergy 2003;58:1059–1063.
80. Jeong KY,Lee J,Lee IY,Ree HI,Hong CS,Yong TS. Analysis of amino acid sequence variations and immunoglobulin E-binding epitopes of German cockroach tropomyosin. Clin Diagn Lab Immunol 2004;11:874–878.
81. Jeong KY,Lee J,Lee IY,Hong CS,Ree HI,Yong TS. Expression of tropomyosin from Blattella germanica as a recombinant nonfusion protein in Pichia pastoris and comparison of its IgE reactivity with its native counterpart. Protein Expr Purif 2004;37:273–278.
82. Jeong KY,Hong CS,Yong TS. Allergenic tropomyosins and their cross-reactivities. Protein Pept Lett 2006;13:835–845.
83. Jeong KY,Hwang H,Lee J,Lee IY,Kim DS,Hong CS,Ree HI,Yong TS. Allergenic characterization of tropomyosin from the dusky brown cockroach, Periplaneta fuliginosa. Clin Diagn Lab Immunol 2004;11:680–685.
84. Ock MS,Kim BJ,Kim SM,Byun KH. Cloning and expression of trypsin-encoding cDNA from Blattella germanica and its possibility as an allergen. Korean J Parasitol 2005;43:101–110.
85. Sudha VT,Arora N,Gaur SN,Pasha S,Singh BP. Identification of a serine protease as a major allergen (Per a 10) of Periplaneta americana. Allergy 2008;63:768–776.
86. Barletta B,Puggioni EM,Afferni C,Butteroni C,Iacovacci P,Tinghino R,Ariano R,Panzani RC,Di Felice G,Pini C. Preparation and characterization of silverfish (Lepisma saccharina) extract and identification of allergenic components. Int Arch Allergy Immunol 2002;128:179–186.
87. Barletta B,Di Felice G,Pini C. Biochemical and molecular biological aspects of silverfish allergens. Protein Pept Lett 2007;14:970–974.
88. Peng Z,Estelle F,Simons R. Mosquito allergy and mosquito salivary allergens. Protein Pept Lett 2007;14:975–981.
89. McCormack DR,Salata KF,Hershey JN,Carpenter GB,Engler RJ. Mosquito bite anaphylaxis: immunotherapy with whole body extracts. Ann Allergy Asthma Immunol 1995;74:39–44.
90. Baur X,Dewair M,Fruhmann G,Aschauer H,Pfletschinger J,Braunitzer G. Hypersensitivity to chironomids (non-biting midges): localization of the antigenic determinants within certain polypeptide sequences of hemoglobins (erythrocruorins) of Chironomus thummi thummi (Diptera). J Allergy Clin Immunol 1982;69:66–76.
91. Yong TS,Lee JS,Lee IY,Park SJ,Park GM,Ree HI,Park JW,Hong CS,Park HS. Identification of Chironomus kiiensis allergens, a dominant species of non-biting midges in Korea. Korean J Parasitol 1999;37:171–179.
92. Jeong KY,Yum HY,Lee IY,Ree HI,Hong CS,Kim DS,Yong TS. Molecular cloning and characterization of tropomyosin, a major allergen of Chironomus kiienesis, a dominant species of nonbiting midges in Korea. Clin Diagn Lab Immunol 2004;11:320–324.
93. Aalberse RC,Akkerdaas J,van Ree R. Cross-reactivity of IgE antibodies to allergens. Allergy 2001;56:478–490.
94. Binder M,Mahler V,Hayek B,Sperr WR,Scholler M,Prozell S,Wiedermann G,Valent P,Valenta R,Duchene M. Molecular and immunological characterization of arginine kinase from the Indianmeal moth, Plodia interpunctella, a novel cross-reactive invertebrate pan-allergen. J Immunol 2001;167:5470–5477.
95. Smith TS,Hogan MB,Welch JE,Corder WT,Wilson NW. Modern prevalence of insect sensitization in rural asthma and allergic rhinitis patients. Allergy Asthma Proc 2005;26:356–360.
96. Kino T,Chihara J,Fukuda K,Sasaki Y,Shogaki Y,Oshima S. Allergy to insects in Japan. III. High frequency of IgE antibody responses to insects (moth, butterfly, caddis fly, and chironomid) in patients with bronchial asthma and immunochemical quantitation of the insect-related airborne particles smaller than 10 microns in diameter. J Allergy Clin Immunol 1987;79:857–866.
97. Yun YY,Ko SH,Park JW,Hong CS. Anaphylaxis to venom of the Pachycondyla species ant. J Allergy Clin Immunol 1999;104:879–882.
98. Kim SS,Park HS,Kim HY,Lee SK,Nahm DH. Anaphylaxis caused by the new ant, Pachycondyla chinensis: demonstration of specific IgE and IgE-binding components. J Allergy Clin Immunol 2001;107:1095–1099.
99. Cho YS,Lee YM,Lee CK,Yoo B,Park HS,Moon HB. Prevalence of Pachycondyla chinensis venom allergy in ant-infested area in Korea. J Allergy Clin Immuol 2002;110:54–57.
100. Lee EK,Jeong KY,Lyu DP,Lee YW,Sohn JH,Lim KJ,Hong CS,Park JW. Characterization of the major allergens of Pachycondyla chinensis in ant sting anaphylaxis patients. Clin Exp Allergy 2009;39:602–607.
101. Kim CW,Choi SY,Park JW,Hong CS. Respiratory allergy to the indoor ant (Monomorium pharaonis) not related to sting allergy. Ann Allergy Asthma Immunol 2005;94:301–306.
102. Bagenstose AH 3rd,Mathews KP,Homburger HA,Saaveard-Delgado AP. Inhalant allergy due to crickets. J Allergy Clin Immunol 1980;65:71–74.
103. Alanko K,Tuomi T,Vanhanen M,Pajari-Backas M,Kanerva L,Havu K,Saarinen K,Bruynzeel DP. Occupational IgE-mediated allergy to Tribolium confusum (confused flour beetle). Allergy 2000;55:879–882.